Many individuals with ACC will also have other changes on their brain scans, such as malformations of the cerebellum, and/or problems in other parts of the body such as the eyes, skin and heart. Not only are these important to identify and treat where necessary, they can also be important clues to the underlying diagnosis. For example, girls with very specific changes on detailed eye examination (called chorioretinal lacunae) in association with brain development abnormalities may have a diagnosis of Aicardi syndrome.