Title: Agenesis of the corpus callosum: prenatal diagnosis and prognosis
Authors: Moutard., M., Kieffer, V., Feingold, J., Kieffer, F., Lewin, F., Adamsbaum., C., Gelot, A., Campistal I Plana, J., van Bogaert, P., Andre, M., Ponst, G.
Journal: Child’s Nervous System, 19, 471-476
Published: 2003
This French study reports on the long-term outcome of children diagnosed with isolated ACC before they were born. A group of 17 children were assessed at ages 2, 4, and 6, although the drop-off rate was high and only seven children were seen at 6 years of age. Most children showed good outcome, with motor skills developing at the expected ages. Intellectual ability was generally within the normal range, although scores varied over time for some children. When the children were of school age subtle cognitive and behaviour problems emerged, particularly in reasoning, slowness, and paying attention. Outcome was not related to whether the child had complete or partial ACC, was male or female, or experienced febrile seizures.