What is Agenesis of the Corpus Callosum?
Agenesis of the Corpus Callosum (ACC) is a rare neurological condition in which the Corpus Callosum, the major “pathway“ for information which links the two hemispheres of the brain, fails to develop fully. The condition is usually diagnosed by CT (Computer Tomographic) or MRI (Magnetic Resonance Imaging) scan.
The effects of the condition are variable; ranging from normal development (where the condition may be undetected or be revealed incidentally), through mild developmental delay to severe learning difficulties, epilepsy, visual impairment and delayed motor development. There may be other brain malformations present, for example microcephaly (small brain) or hydrocephalus (obstruction of the flow of fluid in the head).
What is Aicardi Syndrome?
Aicardi syndrome: a rare syndrome that occurs only in girls (boys are affected only in extremely rare and specific circumstances). Its main features are developmental brain malformations including ACC, seizures, learning difficulties and eye changes (chorioretinal lacunae).
Other problems associated with the condition are spinal or other bone abnormalities and hypotonia (floppiness). The condition is diagnosed by the means of an EEG (electroencephalogram), a brain scan and detailed examination of the eyes by an ophthalmologist (eye specialist).